Cargando…
Hydroxynorketamine: Implications for the NMDA Receptor Hypothesis of Ketamine’s Antidepressant Action
The prevailing hypothesis of ketamine’s unique antidepressant effects implicates N-methyl-d-aspartate receptor (NMDAR) inhibition-dependent enhancement of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated transmission, activation of intracellular signalling pathways and increase...
Autores principales: | Aleksandrova, Lily R., Wang, Yu Tian, Phillips, Anthony G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292673/ https://www.ncbi.nlm.nih.gov/pubmed/30556028 http://dx.doi.org/10.1177/2470547017743511 |
Ejemplares similares
-
S-Ketamine oral thin film—Part 2: Population pharmacodynamics of S-ketamine, S-norketamine and S-hydroxynorketamine
por: Simons, Pieter, et al.
Publicado: (2022) -
S-Ketamine Oral Thin Film—Part 1: Population Pharmacokinetics of S-Ketamine, S-Norketamine and S-Hydroxynorketamine
por: Simons, Pieter, et al.
Publicado: (2022) -
Ketamine Metabolite (2R,6R)-Hydroxynorketamine Interacts with μ and
κ Opioid Receptors
por: Joseph, Thomas T., et al.
Publicado: (2021) -
Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine
por: Shirayama, Yukihiko, et al.
Publicado: (2017) -
The distribution and clearance of (2S,6S)-hydroxynorketamine, an active ketamine metabolite, in Wistar rats
por: Moaddel, Ruin, et al.
Publicado: (2015)