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Molecular pathway analysis towards understanding tissue vulnerability in spinocerebellar ataxia type 1

The neurodegenerative disorder spinocerebellar ataxia type 1 (SCA1) affects the cerebellum and inferior olive, though previous research has focused primarily on the cerebellum. As a result, it is unknown what molecular alterations are present in the inferior olive, and whether these changes are foun...

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Detalles Bibliográficos
Autores principales: Driessen, Terri M, Lee, Paul J, Lim, Janghoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292693/
https://www.ncbi.nlm.nih.gov/pubmed/30507379
http://dx.doi.org/10.7554/eLife.39981