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Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation

As part of PsychENCODE, we developed a three-dimensional (3D) epigenomic map of primary cultured neuronal cells derived from olfactory neuroepithelium (CNON). We mapped topologically associating domains and high-resolution chromatin interactions using Hi-C and identified regulatory elements using ch...

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Detalles Bibliográficos
Autores principales: Rhie, Suhn K., Schreiner, Shannon, Witt, Heather, Armoskus, Chris, Lay, Fides D., Camarena, Adrian, Spitsyna, Valeria N., Guo, Yu, Berman, Benjamin P., Evgrafov, Oleg V., Knowles, James A., Farnham, Peggy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292713/
https://www.ncbi.nlm.nih.gov/pubmed/30555922
http://dx.doi.org/10.1126/sciadv.aav8550