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Association Between Proportion of Nuclei With High Chromatin Entropy and Prognosis in Gynecological Cancers

BACKGROUND: Nuclear texture analysis measuring differences in chromatin structure has provided prognostic biomarkers in several cancers. There is a need for improved cell-by-cell chromatin analysis to detect nuclei with highly disorganized chromatin. The purpose of this study was to develop a method...

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Detalles Bibliográficos
Autores principales: Nielsen, Birgitte, Kleppe, Andreas, Hveem, Tarjei Sveinsgjerd, Pradhan, Manohar, Syvertsen, Rolf Anders, Nesheim, John Arne, Kristensen, Gunnar Balle, Trovik, Jone, Kerr, David James, Albregtsen, Fritz, Danielsen, Håvard Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292794/
https://www.ncbi.nlm.nih.gov/pubmed/29684152
http://dx.doi.org/10.1093/jnci/djy063