Role of the C‐terminus of SUR in the differential regulation of β‐cell and cardiac K(ATP) channels by MgADP and metabolism

KEY POINTS: β‐Cell K(ATP) channels are partially open in the absence of metabolic substrates, whereas cardiac K(ATP) channels are closed. Using cloned channels heterologously expressed in Xenopus oocytes we measured the effect of MgADP on the MgATP concentration–inhibition curve immediately after pa...

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Detalles Bibliográficos
Autores principales: Vedovato, Natascia, Rorsman, Olof, Hennis, Konstantin, Ashcroft, Frances M., Proks, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Molecular and cellular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292810/
https://www.ncbi.nlm.nih.gov/pubmed/30179258
http://dx.doi.org/10.1113/JP276708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292810/
https://www.ncbi.nlm.nih.gov/pubmed/30179258
http://dx.doi.org/10.1113/JP276708

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