Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling

Short chain fatty acids (SCFAs) are protective against inflammatory diseases. Free fatty acid receptor 2 (FFA2), is a target of SCFAs however, their selectivity for FFA2 over other FFA receptors is limited. This study aimed to functionally characterise 2-(4-chlorophenyl)-3-methyl-N-(thiazole-2-yl)bu...

Descripción completa

Detalles Bibliográficos
Autores principales: Schofield, Zoe V., Croker, Daniel, Robertson, Avril A. B., Massey, Nicholas L., Donovan, Chantal, Tee, Ernest, Edwards, David, Woodruff, Trent M., Halai, Reena, Hansbro, Philip M., Cooper, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292860/
https://www.ncbi.nlm.nih.gov/pubmed/30546040
http://dx.doi.org/10.1038/s41598-018-36242-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292860/
https://www.ncbi.nlm.nih.gov/pubmed/30546040
http://dx.doi.org/10.1038/s41598-018-36242-1

Ejemplares similares