Cargando…

Targeted chemotherapy for subcutaneous and orthotopic non-small cell lung tumors with cyclic RGD-functionalized and disulfide-crosslinked polymersomal doxorubicin

Lung cancer, with its high mortality and increasing morbidity, has become one of the most lethal malignancies worldwide. Here, we developed cyclic RGD peptide-directed and disulfide-crosslinked polymersomal doxorubicin (cRGD-PS-Dox) as a targeted chemotherapy for human non-small cell lung cancer (NS...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Yan, Wei, Jingjing, Xia, Yifeng, Meng, Fenghua, Yuan, Jiandong, Zhong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292884/
https://www.ncbi.nlm.nih.gov/pubmed/30564464
http://dx.doi.org/10.1038/s41392-018-0032-7