A yellow fever–Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice

The recent Zika virus (ZIKV) epidemic in the Americas led to an intense search for therapeutics and vaccines. Here we report the engineering of a chimeric virus vaccine candidate (YF-ZIKprM/E) by replacing the antigenic surface glycoproteins and the capsid anchor of YFV-17D with those of a prototypi...

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Detalles Bibliográficos
Autores principales: Kum, Dieudonné B., Mishra, Niraj, Boudewijns, Robbert, Gladwyn-Ng, Ivan, Alfano, Christian, Ma, Ji, Schmid, Michael A., Marques, Rafael E., Schols, Dominique, Kaptein, Suzanne, Nguyen, Laurent, Neyts, Johan, Dallmeier, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292895/
https://www.ncbi.nlm.nih.gov/pubmed/30564463
http://dx.doi.org/10.1038/s41541-018-0092-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292895/
https://www.ncbi.nlm.nih.gov/pubmed/30564463
http://dx.doi.org/10.1038/s41541-018-0092-2

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