Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice

Type 2 diabetes is an age-and-obesity associated disease driven by impairments in glucose homeostasis that ultimately result in defective insulin secretion from pancreatic β-cells. To deconvolve the effects of age and obesity in an experimental model of prediabetes, we fed young and aged mice either...

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Detalles Bibliográficos
Autores principales: De Leon, Elizabeth R., Brinkman, Jacqueline A., Fenske, Rachel J., Gregg, Trillian, Schmidt, Brian A., Sherman, Dawn S., Cummings, Nicole E., Peter, Darby C., Kimple, Michelle E., Lamming, Dudley W., Merrins, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292902/
https://www.ncbi.nlm.nih.gov/pubmed/30546031
http://dx.doi.org/10.1038/s41598-018-36289-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292902/
https://www.ncbi.nlm.nih.gov/pubmed/30546031
http://dx.doi.org/10.1038/s41598-018-36289-0

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