Impact of CFTR modulation with Ivacaftor on Gut Microbiota and Intestinal Inflammation

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Next to progressive airway disease, CF is also associated with intestinal inflammation and dysbiosis. Ivacaftor, a CFTR potentiator, has improved pulmonary and nutritional status but i...

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Detalles Bibliográficos
Autores principales: Ooi, Chee Y., Syed, Saad A., Rossi, Laura, Garg, Millie, Needham, Bronwen, Avolio, Julie, Young, Kelsey, Surette, Michael G., Gonska, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292911/
https://www.ncbi.nlm.nih.gov/pubmed/30546102
http://dx.doi.org/10.1038/s41598-018-36364-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292911/
https://www.ncbi.nlm.nih.gov/pubmed/30546102
http://dx.doi.org/10.1038/s41598-018-36364-6

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