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The formation of chromatin domains involves a primary step based on the 3-D structure of DNA

The general model presented here for the formation of chromatin domains, LADs and TADs, is primarily based on the 3-D structures of the corresponding DNA sequences, the GC-poor and GC-rich isochores. Indeed, the low-heterogeneity GC-poor isochores locally are intrinsically stiff and curved because o...

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Detalles Bibliográficos
Autor principal: Bernardi, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292937/
https://www.ncbi.nlm.nih.gov/pubmed/30546050
http://dx.doi.org/10.1038/s41598-018-35851-0