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Measuring Single-Cell Phenotypic Growth Heterogeneity Using a Microfluidic Cell Volume Sensor

An imaging-integrated microfluidic cell volume sensor was used to evaluate the volumetric growth rate of single cells from a Saccharomyces cerevisiae population exhibiting two phenotypic expression states of the PDR5 gene. This gene grants multidrug resistance by transcribing a membrane transporter...

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Detalles Bibliográficos
Autores principales: Jing, Wenyang, Camellato, Brendan, Roney, Ian J., Kaern, Mads, Godin, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293012/
https://www.ncbi.nlm.nih.gov/pubmed/30546021
http://dx.doi.org/10.1038/s41598-018-36000-3