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Measuring Single-Cell Phenotypic Growth Heterogeneity Using a Microfluidic Cell Volume Sensor
An imaging-integrated microfluidic cell volume sensor was used to evaluate the volumetric growth rate of single cells from a Saccharomyces cerevisiae population exhibiting two phenotypic expression states of the PDR5 gene. This gene grants multidrug resistance by transcribing a membrane transporter...
Autores principales: | Jing, Wenyang, Camellato, Brendan, Roney, Ian J., Kaern, Mads, Godin, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293012/ https://www.ncbi.nlm.nih.gov/pubmed/30546021 http://dx.doi.org/10.1038/s41598-018-36000-3 |
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