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Apolipoprotein E particle size is increased in Alzheimer's disease

INTRODUCTION: Apolipoprotein E4 (apoE4) is the predominant risk factor for late-onset Alzheimer's disease (AD), but the question of which structural differences might explain its effect remains unclear. METHODS: We compared high-density lipoprotein–like apoE particles from 12 AD and 10 control...

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Detalles Bibliográficos
Autores principales: Nelson, Thomas J., Sen, Abhik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293020/
https://www.ncbi.nlm.nih.gov/pubmed/30581971
http://dx.doi.org/10.1016/j.dadm.2018.10.005