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Acquired parvalbumin‐selective interneuronopathy in the multiple‐hit model of infantile spasms: A putative basis for the partial responsiveness to vigabatrin analogs?

West syndrome, an age‐specific epileptic encephalopathy, manifests with infantile spasms (IS) and impaired neurodevelopmental outcomes and epilepsy. The multiple‐hit rat model of IS is a chronic model of IS due to structural etiology, in which spasms respond partially to vigabatrin analogs. Using th...

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Detalles Bibliográficos
Autores principales: Katsarou, Anna‐Maria, Li, Qianyun, Liu, Wei, Moshé, Solomon L., Galanopoulou, Aristea S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293059/
https://www.ncbi.nlm.nih.gov/pubmed/30564774
http://dx.doi.org/10.1002/epi4.12280