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Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Cystic fibrosis (CF) is an inherited disorder where individual disease etiology and response to therapeutic intervention is impacted by CF transmembrane regulator (CFTR) mutations and other genetic modifiers. CFTR regulates multiple mechanisms in a diverse range of epithelial tissues. In this Review...

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Detalles Bibliográficos
Autores principales: Awatade, Nikhil T., Wong, Sharon L., Hewson, Chris K., Fawcett, Laura K., Kicic, Anthony, Jaffe, Adam, Waters, Shafagh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293199/
https://www.ncbi.nlm.nih.gov/pubmed/30581387
http://dx.doi.org/10.3389/fphar.2018.01429