Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase

Mutations in the gene encoding the protein kinase CDKL5 cause a debilitating neurodevelopmental disease termed CDKL5 disorder. The impact of these mutations on CDKL5 function is poorly understood because the substrates and cellular processes controlled by CDKL5 are unclear. Here, we describe a quant...

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Detalles Bibliográficos
Autores principales: Muñoz, Ivan M, Morgan, Michael E, Peltier, Julien, Weiland, Florian, Gregorczyk, Mateusz, Brown, Fiona CM, Macartney, Thomas, Toth, Rachel, Trost, Matthias, Rouse, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293279/
https://www.ncbi.nlm.nih.gov/pubmed/30266825
http://dx.doi.org/10.15252/embj.201899559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293279/
https://www.ncbi.nlm.nih.gov/pubmed/30266825
http://dx.doi.org/10.15252/embj.201899559

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