Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery

The dopaminergic hypothesis of schizophrenia (SZ) postulates that positive symptoms of SZ, in particular psychosis, are due to disturbed neurotransmission via the dopamine (DA) receptor D2 (DRD2). However, DA is a reactive molecule that yields various oxidative species, and thus has important non-re...

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Detalles Bibliográficos
Autores principales: Kos, Mark Z., Duan, Jubao, Sanders, Alan R., Blondell, Lucy, Drigalenko, Eugene I., Carless, Melanie A., Gejman, Pablo V., Göring, Harald H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293320/
https://www.ncbi.nlm.nih.gov/pubmed/30546022
http://dx.doi.org/10.1038/s41398-018-0325-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293320/
https://www.ncbi.nlm.nih.gov/pubmed/30546022
http://dx.doi.org/10.1038/s41398-018-0325-1

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