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Improving pharmacogenetic prediction of extrapyramidal symptoms induced by antipsychotics

In previous work we developed a pharmacogenetic predictor of antipsychotic (AP) induced extrapyramidal symptoms (EPS) based on four genes involved in mTOR regulation. The main objective is to improve this predictor by increasing its biological plausibility and replication. We re-sequence the four ge...

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Detalles Bibliográficos
Autores principales: Boloc, Daniel, Gortat, Anna, Cheng-Zhang, Jia Qi, García-Cerro, Susana, Rodríguez, Natalia, Parellada, Mara, Saiz-Ruiz, Jeronimo, Cuesta, Manolo J., Gassó, Patricia, Lafuente, Amalia, Bernardo, Miquel, Mas, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293322/
https://www.ncbi.nlm.nih.gov/pubmed/30546092
http://dx.doi.org/10.1038/s41398-018-0330-4