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Improving pharmacogenetic prediction of extrapyramidal symptoms induced by antipsychotics
In previous work we developed a pharmacogenetic predictor of antipsychotic (AP) induced extrapyramidal symptoms (EPS) based on four genes involved in mTOR regulation. The main objective is to improve this predictor by increasing its biological plausibility and replication. We re-sequence the four ge...
Autores principales: | Boloc, Daniel, Gortat, Anna, Cheng-Zhang, Jia Qi, García-Cerro, Susana, Rodríguez, Natalia, Parellada, Mara, Saiz-Ruiz, Jeronimo, Cuesta, Manolo J., Gassó, Patricia, Lafuente, Amalia, Bernardo, Miquel, Mas, Sergi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293322/ https://www.ncbi.nlm.nih.gov/pubmed/30546092 http://dx.doi.org/10.1038/s41398-018-0330-4 |
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