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A genome-wide dsRNA library screen for Drosophila genes that regulate the GBP/phospholipase C signaling axis that links inflammation to aging

OBJECTIVE: Invertebrates are productive models for understanding how inflammation, metabolism and aging are intertwined. We have deployed a dsRNA library screen to search for genes in Drosophila melanogaster—and hence identify human orthologs—that encode participants in a G-protein coupled, Ca(2+)-s...

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Detalles Bibliográficos
Autores principales: Sung, Eui Jae, Shears, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293519/
https://www.ncbi.nlm.nih.gov/pubmed/30545410
http://dx.doi.org/10.1186/s13104-018-3996-z