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Modeling the quantitative nature of neurodevelopmental disorders using Collaborative Cross mice
BACKGROUND: Animal models for neurodevelopmental disorders (NDD) generally rely on a single genetic mutation on a fixed genetic background. Recent human genetic studies however indicate that a clinical diagnosis with ASDAutism Spectrum Disorder (ASD) is almost always associated with multiple genetic...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293525/ https://www.ncbi.nlm.nih.gov/pubmed/30559955 http://dx.doi.org/10.1186/s13229-018-0252-2 |