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Modeling the quantitative nature of neurodevelopmental disorders using Collaborative Cross mice

BACKGROUND: Animal models for neurodevelopmental disorders (NDD) generally rely on a single genetic mutation on a fixed genetic background. Recent human genetic studies however indicate that a clinical diagnosis with ASDAutism Spectrum Disorder (ASD) is almost always associated with multiple genetic...

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Detalles Bibliográficos
Autores principales: Molenhuis, Remco T., Bruining, Hilgo, Brandt, Myrna J. V., van Soldt, Petra E., Abu-Toamih Atamni, Hanifa J., Burbach, J. Peter H., Iraqi, Fuad A., Mott, Richard F., Kas, Martien J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293525/
https://www.ncbi.nlm.nih.gov/pubmed/30559955
http://dx.doi.org/10.1186/s13229-018-0252-2