ErbB2-driven downregulation of the transcription factor Irf6 in breast epithelial cells is required for their 3D growth

BACKGROUND: The ability of solid tumor cells to resist anoikis, apoptosis triggered by cell detachment from the extracellular matrix (ECM), is thought to be critical for 3D tumor growth. ErbB2/Her2 oncoprotein is often overproduced by breast tumor cells and blocks their anoikis by partially understo...

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Detalles Bibliográficos
Autores principales: Khan, Iman Aftab, Yoo, Byong Hoon, McPhee, Michael, Masson, Olivier, Surette, Alexi, Dakin-Hache, Kelly, Younis, Tallal, Bethune, Gillian, Rosen, Kirill V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293553/
https://www.ncbi.nlm.nih.gov/pubmed/30545388
http://dx.doi.org/10.1186/s13058-018-1080-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293553/
https://www.ncbi.nlm.nih.gov/pubmed/30545388
http://dx.doi.org/10.1186/s13058-018-1080-1

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