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Metformin regulates atrial SK2 and SK3 expression through inhibiting the PKC/ERK signaling pathway in type 2 diabetic rats
BACKGROUND: Our previous study showed that metformin regulates the mRNA and protein levels of type 2 small conductance calcium-activated potassium channel (SK2) and type 3 small conductance calcium-activated potassium channels (SK3) in atrial tissue as well as the ion current of atrial myocytes in r...
Autores principales: | Liu, Chang-He, Hua, Na, Fu, Xi, Pan, Yi-Long, Li, Bin, Li, Xiao-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293565/ https://www.ncbi.nlm.nih.gov/pubmed/30545309 http://dx.doi.org/10.1186/s12872-018-0950-x |
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