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Long non-coding RNA HIF1A-AS2 facilitates adipose-derived stem cells (ASCs) osteogenic differentiation through miR-665/IL6 axis via PI3K/Akt signaling pathway

BACKGROUND: This study was aimed to investigate the role and specific molecular mechanism of HIF1A-AS2/miR-665/IL6 axis in regulating osteogenic differentiation of adipose-derived stem cells (ASCs) via the PI3K/Akt signaling pathway. METHODS: RNAs’ expression profile in normal/osteogenic differentia...

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Detalles Bibliográficos
Autores principales: Wu, Ruoyu, Ruan, Jihao, Sun, Yongjin, Liu, Mengyu, Sha, Zhuang, Fan, Cunyi, Wu, Qingkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293597/
https://www.ncbi.nlm.nih.gov/pubmed/30545407
http://dx.doi.org/10.1186/s13287-018-1082-z