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Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

BACKGROUND: The molecular signaling events involving in high malignancy and poor prognosis of hepatocellular carcinoma (HCC) are extremely complicated. Blockade of currently known targets has not yet led to successful clinical outcome. More understanding about the regulatory mechanisms in HCC is nec...

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Detalles Bibliográficos
Autores principales: Dai, Bin, Zhang, Xuan, Shang, Runze, Wang, Jianlin, Yang, Xisheng, Zhang, Hong, Liu, Qi, Wang, Desheng, Wang, Lin, Dou, Kefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293628/
https://www.ncbi.nlm.nih.gov/pubmed/30545369
http://dx.doi.org/10.1186/s12964-018-0312-4