The addition of avibactam renders piperacillin an effective treatment for Mycobacterium abscessus infection in an in vivo model

Treating M. abscessus infection is challenging due to the potent β-lactamase Bla(Mab) (Beta-lactamase of M. abscessus()). Avibactam is a non-β-lactam, β-lactamase inhibitor shown to inhibit Bla(Mab). We tested whether avibactem can render piperacillin effective against M. Abscessus. In-vitro, avibac...

Descripción completa

Detalles Bibliográficos
Autores principales: Meir, Michal, Bifani, Pablo, Barkan, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293638/
https://www.ncbi.nlm.nih.gov/pubmed/30564307
http://dx.doi.org/10.1186/s13756-018-0448-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293638/
https://www.ncbi.nlm.nih.gov/pubmed/30564307
http://dx.doi.org/10.1186/s13756-018-0448-4

Ejemplares similares