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The addition of avibactam renders piperacillin an effective treatment for Mycobacterium abscessus infection in an in vivo model
Treating M. abscessus infection is challenging due to the potent β-lactamase Bla(Mab) (Beta-lactamase of M. abscessus()). Avibactam is a non-β-lactam, β-lactamase inhibitor shown to inhibit Bla(Mab). We tested whether avibactem can render piperacillin effective against M. Abscessus. In-vitro, avibac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293638/ https://www.ncbi.nlm.nih.gov/pubmed/30564307 http://dx.doi.org/10.1186/s13756-018-0448-4 |