The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer

BACKGROUND: The study aims to present the effect of PIK3CA E542K and E545K mutations on glucose metabolism and proliferation and identify their underlying mechanisms in cervical cancer. METHODS: The maximum standard uptake value (SUV(max)) of tumors was detected by(18)F-FDG PET/CT scan. In vitro, gl...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Wei, He, Tiancong, Liu, Shuai, Zheng, Yingying, Xiang, Libing, Pei, Xuan, Wang, Ziliang, Yang, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293652/
https://www.ncbi.nlm.nih.gov/pubmed/30547809
http://dx.doi.org/10.1186/s13045-018-0674-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293652/
https://www.ncbi.nlm.nih.gov/pubmed/30547809
http://dx.doi.org/10.1186/s13045-018-0674-5

Ejemplares similares