Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways

BACKGROUND: Human myeloma cell lines (HMCLs) are widely used for their representation of primary myeloma cells because they cover patient diversity, although not fully. Their genetic background is mostly undiscovered, and no comprehensive study has ever been conducted in order to reveal those detail...

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Detalles Bibliográficos
Autores principales: Tessoulin, Benoît, Moreau-Aubry, Agnès, Descamps, Géraldine, Gomez-Bougie, Patricia, Maïga, Sophie, Gaignard, Alban, Chiron, David, Ménoret, Emmanuelle, Le Gouill, Steven, Moreau, Philippe, Amiot, Martine, Pellat-Deceunynck, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293660/
https://www.ncbi.nlm.nih.gov/pubmed/30545397
http://dx.doi.org/10.1186/s13045-018-0679-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293660/
https://www.ncbi.nlm.nih.gov/pubmed/30545397
http://dx.doi.org/10.1186/s13045-018-0679-0

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