Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling

Wnt/Wg-signalling is critical signalling in all metazoans. Recent studies suggest that IFT-A proteins and Kinesin-2 modulate canonical Wnt/Wg-signalling independently of their ciliary role. Whether they function together in Wnt-signalling and their mechanistic role in the pathway remained unresolved...

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Detalles Bibliográficos
Autores principales: Vuong, Linh T., Iomini, Carlo, Balmer, Sophie, Esposito, Davide, Aaronson, Stuart A., Mlodzik, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294004/
https://www.ncbi.nlm.nih.gov/pubmed/30546012
http://dx.doi.org/10.1038/s41467-018-07605-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294004/
https://www.ncbi.nlm.nih.gov/pubmed/30546012
http://dx.doi.org/10.1038/s41467-018-07605-z

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