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Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling

Wnt/Wg-signalling is critical signalling in all metazoans. Recent studies suggest that IFT-A proteins and Kinesin-2 modulate canonical Wnt/Wg-signalling independently of their ciliary role. Whether they function together in Wnt-signalling and their mechanistic role in the pathway remained unresolved...

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Detalles Bibliográficos
Autores principales:	Vuong, Linh T., Iomini, Carlo, Balmer, Sophie, Esposito, Davide, Aaronson, Stuart A., Mlodzik, Marek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294004/ https://www.ncbi.nlm.nih.gov/pubmed/30546012 http://dx.doi.org/10.1038/s41467-018-07605-z

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