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MoVE identifies metabolic valves to switch between phenotypic states

Metabolism is highly regulated, allowing for robust and complex behavior. This behavior can often be achieved by controlling a small number of important metabolic reactions, or metabolic valves. Here, we present a method to identify the location of such valves: the metabolic valve enumerator (MoVE)....

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Detalles Bibliográficos
Autores principales: Venayak, Naveen, von Kamp, Axel, Klamt, Steffen, Mahadevan, Radhakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294006/
https://www.ncbi.nlm.nih.gov/pubmed/30552335
http://dx.doi.org/10.1038/s41467-018-07719-4