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Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development

Oocyte-specific miRNA function remains unclear in mice and worms because loss of Dgcr8 and Dicer from mouse and worm oocytes, respectively, does not yield oogenic defects. These data lead to several models: (a) miRNAs are not generated in oocytes; (b) miRNAs are generated but do not perform an oogen...

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Detalles Bibliográficos
Autores principales: Minogue, Amanda L., Tackett, Michael R., Atabakhsh, Elnaz, Tejada, Genesis, Arur, Swathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294007/
https://www.ncbi.nlm.nih.gov/pubmed/30552320
http://dx.doi.org/10.1038/s41467-018-07791-w