Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines

HIV-1-infected people who take drugs that suppress viremia to undetectable levels are protected from developing AIDS. Nonetheless, HIV-1 establishes proviruses in long-lived CD4(+) memory T cells, and perhaps other cell types, that preclude elimination of the virus even after years of continuous ant...

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Detalles Bibliográficos
Autores principales: McCauley, Sean Matthew, Kim, Kyusik, Nowosielska, Anetta, Dauphin, Ann, Yurkovetskiy, Leonid, Diehl, William Edward, Luban, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294009/
https://www.ncbi.nlm.nih.gov/pubmed/30546110
http://dx.doi.org/10.1038/s41467-018-07753-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294009/
https://www.ncbi.nlm.nih.gov/pubmed/30546110
http://dx.doi.org/10.1038/s41467-018-07753-2

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