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Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines
HIV-1-infected people who take drugs that suppress viremia to undetectable levels are protected from developing AIDS. Nonetheless, HIV-1 establishes proviruses in long-lived CD4(+) memory T cells, and perhaps other cell types, that preclude elimination of the virus even after years of continuous ant...
Autores principales: | McCauley, Sean Matthew, Kim, Kyusik, Nowosielska, Anetta, Dauphin, Ann, Yurkovetskiy, Leonid, Diehl, William Edward, Luban, Jeremy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294009/ https://www.ncbi.nlm.nih.gov/pubmed/30546110 http://dx.doi.org/10.1038/s41467-018-07753-2 |
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