Implication for alphavirus host-cell entry and assembly indicated by a 3.5Å resolution cryo-EM structure

Alphaviruses are enveloped RNA viruses that contain several human pathogens. Due to intrinsic heterogeneity of alphavirus particles, a high resolution structure of the virion is currently lacking. Here we provide a 3.5 Å cryo-EM structure of Sindbis virus, using block based reconstruction method tha...

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Detalles Bibliográficos
Autores principales: Chen, Lihong, Wang, Ming, Zhu, Dongjie, Sun, Zhenzhao, Ma, Jun, Wang, Jinglin, Kong, Lingfei, Wang, Shida, Liu, Zaisi, Wei, Lili, He, Yuwen, Wang, Jingfei, Zhang, Xinzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294011/
https://www.ncbi.nlm.nih.gov/pubmed/30552337
http://dx.doi.org/10.1038/s41467-018-07704-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294011/
https://www.ncbi.nlm.nih.gov/pubmed/30552337
http://dx.doi.org/10.1038/s41467-018-07704-x

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