Genome Toxicity and Impaired Stem Cell Function after Conditional Activation of CreER(T2) in the Intestine

With the tamoxifen-inducible CreER(T2) system, genetic recombination can be temporally controlled in a cell-type-specific manner in intact animals, permitting dissection of the molecular underpinnings of mammalian physiology. Here we present a significant drawback to CreER(T2) technology for analysi...

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Detalles Bibliográficos
Autores principales: Bohin, Natacha, Carlson, Elizabeth A., Samuelson, Linda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294112/
https://www.ncbi.nlm.nih.gov/pubmed/30449703
http://dx.doi.org/10.1016/j.stemcr.2018.10.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294112/
https://www.ncbi.nlm.nih.gov/pubmed/30449703
http://dx.doi.org/10.1016/j.stemcr.2018.10.014

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