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Specifying the Anterior Primitive Streak by Modulating YAP1 Levels in Human Pluripotent Stem Cells

Specifying the primitive streak (PS) guides stem cell differentiation in vitro; however, much remains to be learned about the transcription networks that direct anterior and posterior PS cells (APS and PPS, respectively) to differentiate to distinct mesendodermal subpopulations. Here, we show that A...

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Detalles Bibliográficos
Autores principales: Hsu, Hui-Ting, Estarás, Conchi, Huang, Ling, Jones, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294113/
https://www.ncbi.nlm.nih.gov/pubmed/30449705
http://dx.doi.org/10.1016/j.stemcr.2018.10.013