Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies

The small intestine plays an important role in the absorption and metabolism of oral drugs. In the current evaluation system, it is difficult to predict the precise absorption and metabolism of oral drugs. In this study, we generated small intestinal epithelial-like cells from human induced pluripot...

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Detalles Bibliográficos
Autores principales: Negoro, Ryosuke, Takayama, Kazuo, Kawai, Kanae, Harada, Kazuo, Sakurai, Fuminori, Hirata, Kazumasa, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294172/
https://www.ncbi.nlm.nih.gov/pubmed/30472010
http://dx.doi.org/10.1016/j.stemcr.2018.10.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294172/
https://www.ncbi.nlm.nih.gov/pubmed/30472010
http://dx.doi.org/10.1016/j.stemcr.2018.10.019

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