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Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies
The small intestine plays an important role in the absorption and metabolism of oral drugs. In the current evaluation system, it is difficult to predict the precise absorption and metabolism of oral drugs. In this study, we generated small intestinal epithelial-like cells from human induced pluripot...
Autores principales: | Negoro, Ryosuke, Takayama, Kazuo, Kawai, Kanae, Harada, Kazuo, Sakurai, Fuminori, Hirata, Kazumasa, Mizuguchi, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294172/ https://www.ncbi.nlm.nih.gov/pubmed/30472010 http://dx.doi.org/10.1016/j.stemcr.2018.10.019 |
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