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Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells

Nicotinamide, the amide form of vitamin B3, is widely used in disease treatments and stem cell applications. However, nicotinamide's impact often cannot be attributed to its nutritional functions. In a vitamin screen, we find that nicotinamide promotes cell survival and differentiation in human...

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Detalles Bibliográficos
Autores principales: Meng, Ya, Ren, Zhili, Xu, Faxiang, Zhou, Xiaoxiao, Song, Chengcheng, Wang, Vivien Ya-Fan, Liu, Weiwei, Lu, Ligong, Thomson, James A., Chen, Guokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294242/
https://www.ncbi.nlm.nih.gov/pubmed/30503259
http://dx.doi.org/10.1016/j.stemcr.2018.10.023