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Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells
Nicotinamide, the amide form of vitamin B3, is widely used in disease treatments and stem cell applications. However, nicotinamide's impact often cannot be attributed to its nutritional functions. In a vitamin screen, we find that nicotinamide promotes cell survival and differentiation in human...
Autores principales: | Meng, Ya, Ren, Zhili, Xu, Faxiang, Zhou, Xiaoxiao, Song, Chengcheng, Wang, Vivien Ya-Fan, Liu, Weiwei, Lu, Ligong, Thomson, James A., Chen, Guokai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294242/ https://www.ncbi.nlm.nih.gov/pubmed/30503259 http://dx.doi.org/10.1016/j.stemcr.2018.10.023 |
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