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Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM

Glioblastoma multiforme (GBM) remains a cancer with a poor prognosis and few effective therapeutic options. Successful medical management of GBM is limited by the restricted access of drugs to the central nervous system (CNS) caused by the blood brain barrier (BBB). We previously showed that a subse...

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Detalles Bibliográficos
Autores principales: Przystal, Justyna Magdalena, Hajji, Nabil, Khozoie, Combiz, Renziehausen, Alexander, Zeng, Qingyu, Abaitua, Fernando, Hajitou, Amin, Suwan, Keittisak, Want, Elizabeth, Bomalaski, John, Szlosarek, Peter, O’Neill, Kevin, Crook, Tim, Syed, Nelofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294248/
https://www.ncbi.nlm.nih.gov/pubmed/30546006
http://dx.doi.org/10.1038/s41419-018-1195-4