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Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALS

Spinal motor axons traverse large distances to innervate target muscles, thus requiring local control of cellular events for proper functioning. To interrogate axon-specific processes we developed Axon-seq, a refined method incorporating microfluidics, RNA sequencing (RNA-seq), and bioinformatic qua...

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Detalles Bibliográficos
Autores principales: Nijssen, Jik, Aguila, Julio, Hoogstraaten, Rein, Kee, Nigel, Hedlund, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294264/
https://www.ncbi.nlm.nih.gov/pubmed/30540963
http://dx.doi.org/10.1016/j.stemcr.2018.11.005