The transcription factor c-Maf is essential for the commitment of IL-17-producing γδ T cells

γδ T cells that produce the cytokine IL-17 (Tγδ17 cells) are innate-like mediators of immunity that undergo effector programming in the thymus. While regulators of Tγδ17 specialization restricted to various Vγ subsets are known, a commitment factor essential to all Tγδ17 cells has remained undefined...

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Detalles Bibliográficos
Autores principales: Zuberbuehler, Matthew K., Parker, Morgan E., Wheaton, Joshua D., Espinosa, Jaclyn R., Salzler, Harmony R., Park, Eunchong, Ciofani, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294311/
https://www.ncbi.nlm.nih.gov/pubmed/30538336
http://dx.doi.org/10.1038/s41590-018-0274-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294311/
https://www.ncbi.nlm.nih.gov/pubmed/30538336
http://dx.doi.org/10.1038/s41590-018-0274-0

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