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Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Spatial mapping is a promising strategy to investigate the mechanisms underlying the incidence of psychosis. We analyzed a case-cohort study (n = 24,028), drawn from the 1.47 million Danish persons born between 1981 and 2005, using a novel framework for decomposing the geospatial risk for schizophre...

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Detalles Bibliográficos
Autores principales: Fan, Chun Chieh, McGrath, John J., Appadurai, Vivek, Buil, Alfonso, Gandal, Michael J., Schork, Andrew J., Mortensen, Preben Bo, Agerbo, Esben, Geschwind, Sandy A., Geschwind, Daniel, Werge, Thomas, Thompson, Wesley K., Pedersen, Carsten Bøcker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294340/
https://www.ncbi.nlm.nih.gov/pubmed/30546018
http://dx.doi.org/10.1038/s41467-018-07708-7