Toll-like receptor chaperone HSP90B1 and the immune response to Mycobacteria

RATIONALE: HSP90B1, also known as gp96, is a chaperone for multiple Toll-like receptors (TLRs) and is necessary for TLR-mediated inflammatory responses in murine myeloid cells. The molecule is also expressed in T-cells though its specific role is unknown. We hypothesized that human HSP90B1 regulates...

Descripción completa

Detalles Bibliográficos
Autores principales: Graustein, Andrew D., Misch, Elizabeth A., Musvosvi, Munyaradzi, Shey, Muki, Shah, Javeed A., Seshadri, Chetan, Aguoju, Augustine, Bowman, Kathryn, Mulenga, Humphrey, Veldsman, Ashley, Hanekom, Willem A., Hatherill, Mark, Scriba, Thomas J., Hawn, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294361/
https://www.ncbi.nlm.nih.gov/pubmed/30550567
http://dx.doi.org/10.1371/journal.pone.0208940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294361/
https://www.ncbi.nlm.nih.gov/pubmed/30550567
http://dx.doi.org/10.1371/journal.pone.0208940

Ejemplares similares