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A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

LIM kinases are located at a strategic crossroad, downstream of several signaling pathways and upstream of effectors such as microtubules and the actin cytoskeleton. Cofilin is the only LIM kinases substrate that is well described to date, and its phosphorylation on serine 3 by LIM kinases controls...

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Detalles Bibliográficos
Autores principales: Prudent, Renaud, Demoncheaux, Nathalie, Diemer, Hélène, Collin-Faure, Véronique, Kapur, Reuben, Paublant, Fabrice, Lafanechère, Laurence, Cianférani, Sarah, Rabilloud, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294390/
https://www.ncbi.nlm.nih.gov/pubmed/30550596
http://dx.doi.org/10.1371/journal.pone.0208979