Cargando…

Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress

Intracellular pathogens must egress from the host cell to continue their infectious cycle. Apicomplexans are a phylum of intracellular protozoans that have evolved members of the membrane attack complex and perforin (MACPF) family of pore forming proteins to disrupt cellular membranes for traversing...

Descripción completa

Detalles Bibliográficos
Autores principales: Guerra, Alfredo J., Zhang, Ou, Bahr, Constance M. E., Huynh, My-Hang, DelProposto, James, Brown, William C., Wawrzak, Zdzislaw, Koropatkin, Nicole M., Carruthers, Vern B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294395/
https://www.ncbi.nlm.nih.gov/pubmed/30513119
http://dx.doi.org/10.1371/journal.ppat.1007476